Home
About Journal
AHEAD OF PRINT
Current Issue
Back Issues
Instructions
Submission
Search
Subscribe
Blog
Reader Login
Users Online:
995
Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
Access statistics : Table of Contents
2009| October-December | Volume 43 | Issue 4
Online since
September 23, 2009
Archives
Previous Issue
Next Issue
Most popular articles
Most cited articles
Show all abstracts
Show selected abstracts
Export selected to
Viewed
PDF
Cited
ORIGINAL ARTICLES
Evaluation of the clinical signs of anterior cruciate ligament and meniscal injuries
Dhavalakumar K Jain, Rajkumar Amaravati, Gaurav Sharma
October-December 2009, 43(4):375-378
DOI
:10.4103/0019-5413.55466
PMID
:19838388
Background:
The diagnostic accuracy of anterior drawer (AD) sign, Lachman test and the pivot shift test for anterior cruciate ligament injury and McMurray test for medial and lateral meniscus is varied with sensitivity and specificity ranging from 2 to 100%. Generally, it is accepted that the pivot shift test is the most specific test to diagnose anterior cruciate ligament (ACL) tears and that the Lachman test is more sensitive than AD sign. This study was undertaken to calculate the sensitivity, specificity, positive predictive value, negative predictive value, and efficiency for the above-mentioned diagnostic tests.
Materials and Methods:
Twenty-eight male patients with clinical ACL injury were examined in the outpatient department and under anaesthesia, the findings were compared with arthroscopy.
Result:
The sensitivity and specificity for the Lachman test, AD sign and pivot shift test performed in the outpatient setting are 78.6 and 100%, 89.3 and 100%, and 75 and 100%, respectively. The sensitivity and specificity for the Lachman test, AD sign, and pivot shift test performed under anesthesia are 92.9 and 100%, 92.9 and 100%, and 100 and 100%, respectively. The sensitivity and specificity of the McMurray test for medial and lateral meniscus were 35.7 and 85.7% and 22.2 and 100%, respectively.
Conclusion:
The Lachman test, AD sign and pivot shift test are highly specific tests to diagnose ACL laxity in a non-acute setting; pivot shift test under anesthesia is the most sensitive and specific test for diagnosing ACL laxity in a non-acute setting and the McMurray test is not a sensitive test to diagnose meniscal injury in the presence of ACL injury.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
7,166
597
6
Use of antibiotic cement-impregnated intramedullary nail in treatment of infected non-union of long bone
Ashok K Shyam, Parag K Sancheti, Salim K Patel, Steve Rocha, Chetan Pradhan, Atul Patil
October-December 2009, 43(4):396-402
DOI
:10.4103/0019-5413.55468
PMID
:19838392
Background:
In cases with infected non-union, the primary step is eradication of the infection before attempting to achieve union. Release of antibiotics from the bone cement at a high concentration and its penetration to the surrounding tissues, including cortical and cancellous bone, prompted the use of antibiotic cement in the control of bone infection. The aim of this study is to summarize our experience with the use of antibiotic cement-impregnated intramedullary nail (ACIIN) for control of infection in cases of infected non-union with bone defect.
Materials and Methods:
We prospectively studied 25 cases of infected non-union (23 femora and two tibiae). There were 24 males and one female, with the mean age being 33 years (range, 21-58 years). All patients had high-velocity road traffic accidents except one patient who had farmland injury. There were seven closed fractures, one grade I compound, two grade II compound fractures, five grade IIIA compound fractures, and 10 grade IIIB compound fractures. ACIIN was used in all cases after adequate debridement. Patients were classified according to the amount of bone defect present after debridement: group 1 with bone defect <4 cm (n=13), group 2 with bone defect ≥4-<6 cm (n=7), and group 3 with bone defect ≥6 cm (n=5). Infection control was judged on the basis of discharge through the wound and laboratory parameters. All patients were followed-up, with an average follow-up time of 29 months (range, 18-40 months). The mean duration of retention of the intramedullary rod was 8 weeks (range, 6-12 weeks).
Results:
In group 1, all cases achieved infection control, with three patients achieving bone union without any need of secondary procedure. In group 2, all cases achieved infection control but the time taken was significantly longer than for group 1 (p-value 0.0002). All the cases required a secondary procedure in the form of either interlocking intramedullary nailing with iliac crest bone graft or Ilizarov ring fixator application to achieve union. None of the cases in group 3 achieved infection control.
Conclusion:
ACIINs are useful for infection control in cases of infected non-union with bone defect <6 cm. In cases with defect >6 cm, other alternatives should be used.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
5,719
805
14
Missed Monteggia fracture in children: Is annular ligament reconstruction always required?
Atul Bhaskar
October-December 2009, 43(4):389-395
DOI
:10.4103/0019-5413.55978
PMID
:19838391
Background:
Chronic (neglected) radiocapitellar joint dislocation is one of the feared complications of Monteggia fractures especially when associated with subtle fracture of the ulna bone. Many treatment strategies have been described to manage chronic Monteggia fracture and the need for annular ligament reconstruction is not always clear. The purpose of this study is to highlight the management of missed Monteggia fracture with particular emphasis on utility of annular ligament reconstruction by comparing the two groups of patients.
Materials and Methods:
In a prospective study 12 patients with mean age of 7.4 years, who presented with neglected Monteggia fractures, were studied. All children underwent open reduction of the radiocapitellar joint. Five children (Group A) were treated with angulation-distraction osteotomy of ulna and annular ligament reconstruction and six cases (Group B) required only angulation-distraction osteotomy of ulna without ligament reconstruction. In one case an open reduction of the radiocapitellar joint was sufficient to reduce the radial head and this was included in Group B. The gap between injury and presentation was from 3 months to 18 months (mean 9 months). Ten patients were classified as Bado I, and one each as Bado II and III respectively. We used the Kim's criteria to score our results.
Result:
The mean follow-up period was 22 months. All ulna osteotomies healed uneventfully. The mean loss of pronation was 15 degree in Group A and 10 degree in Group B. Elbow flexion improved from the preoperative range and no child complained of pain, deformity and restriction of activity. The elbow score was excellent in 10 cases, and good in two cases.
Conclusion:
Distraction-angulation osteotomy of the ulna suffices in most cases of missed monteggia fracture and the need for annular ligament reconstruction is based on intraoperative findings of radial head instability.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
6,032
484
16
Unicompartmental knee arthroplasty for tricompartment osteoarthritis in octogenarians
SKS Marya, Rajiv Thukral
October-December 2009, 43(4):361-366
DOI
:10.4103/0019-5413.54970
PMID
:19838386
Background:
Unicompartmental knee arthroplasty (UKA) is specifically indicated in isolated unicompartmental arthritis with competent ligaments. Recent series of UKA for unicompartmental arthritis have shown good function, persistence of pain relief, and nearly 90% survivorship at 15 years, even in knees that would perhaps not be considered good indications for UKA today. The perioperative morbidity of UKA is less than total knee arthroplasty. We present our series of 19 octogenarians with tricompartment osteoarthritis (predominant medial compartment involvement) treated with UKA as definitive surgery.
Materials and Methods:
We performed UKA on 29 knees (19 patients) average 83 years (79-94 years) of either sex from Jan 2002 to Dec 2006. All the patients had tricompartment knee osteoarthritis (with predominant medial and some patellofemoral compartment involvement).
Results:
The results were evaluated using the Knee Society scores and visual analogue score over an average 48-month follow-up (range, 24 to 81 months). Barring one (medial femoral condyle fracture detected on postoperative radiography), all patients achieved promised levels of satisfaction.
Discussion:
UKA for tricompartment knee arthritis in the young active patient entails risk of dissatisfaction and failure. We present UKA in select 'very elderly' patients with tricompartment osteoarthritis (with predominant unicompartment involvement).
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
5,754
269
6
PERSPECTIVES
Basic research in orthopedic surgery: Current trends and future directions
Chuanyong Lu, Jenni M Buckley, Celine Colnot, Ralph Marcucio, Theodore Miclau
October-December 2009, 43(4):318-323
DOI
:10.4103/0019-5413.55969
PMID
:19838378
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,146
569
3
ORIGINAL ARTICLES
The INDUS knee prosthesis - Prospective multicentric trial of a posteriorly stabilized high-flex design: 2 years follow-up
Kantilal H Sancheti, Nandu S Laud, Harish Bhende, Gurava Reddy, Neema Pramod, Joseph N Mani
October-December 2009, 43(4):367-374
DOI
:10.4103/0019-5413.55976
PMID
:19838387
Background:
The anatomical and morphological differences and high-flexion daily activities in the Asian population have since ever prompted for development of customized knee replacement systems. INDUS knee system has advantages both of high-flex designs and is developed by keeping the anatomical variations of the native population in mind. The purpose of this study is to analyze the 2-year follow-up results using the INDUS prosthesis.
Materials and Methods:
Two hundred and ninety-seven knees in 276 patients were prospectively analyzed. There were 65 men (72 knees) and 211 (225 knees) women with a mean age of 64.56 years. Two hundred and forty-five knees had primary osteoarthritis, 48 knees had rheumatoid arthritis, and four knees had post-traumatic arthritis. Clinical parameters, including the Knee Society scores (knee score and function score), range of motion, post-operative anterior knee pain, and complications were recorded. Pre- and post-operative serial radiographs were analyzed for limb alignment, component positioning, and evidence of loosening.
Results:
The patients were followed-up for an average of 2.59 years (range, 2-3.3 years). The mean knee score and the mean function score were significantly improved from a pre-operative value of 39.4 points and 46.7 points to a post-operative value of 87 points and 86 points, respectively (
P
value <0.05). Two hundred and thirty four knees had no anterior knee pain while 63 knees had mild to moderate pain, but none of the patients requested any intervention for the same. Of the 276 patients (297 knees), 79 knees had flexion above 140°, 167 had a flexion range of 130-140°, 27 had a flexion range of 100-130°, and 24 knees had a flexion <100°, with the mean range of movement being 132.9°. Improvements in the range of movement were retained over time and a total of 205 patients (224 knees, 75.7%) could squat or sit cross-legged at the final follow-up. The mean tibiofemoral angle was 8.5°± 6.9º of varus pre-operatively and 5.4°± 2.2º of valgus (3-7° of valgus) at the final follow-up, with no loss of alignment noted in any case. One knee underwent revision for late infection while another knee had periprosthetic supracondylar fracture treated with plate fixation.
Conclusions:
Use of the INDUS knee prosthesis has a favorable short-term outcome, with a mean range of 135° flexion and excellent knee scores.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,140
422
9
Odontoid fractures: A retrospective analysis of 53 cases
Arjun Shetty, Abhishek R Kini, Jagadish Prabhu
October-December 2009, 43(4):352-360
DOI
:10.4103/0019-5413.55975
PMID
:19838385
Background:
The management of odontoid fracture has evolved but controversy persists as to the best method for Type II odontoid fractures with or without atlantoaxial (AA) instability. The anterior odontoid screw fixation can be associated with significant morbidity while delayed odontoid screw fixation has shown to be associated with reasonable good fusion rates. We conducted a retrospective analysis to evaluate the outcome of a trial of conservative management in type II odontoid fractures without atlantoaxial instability (Group A) followed by delayed odontoid screw fixation in cases in which fusion was not achieved by conservative treatment. The outcome of type II odontoid fracture with AA subluxation (Group B) was also analysed where closed reduction on traction could be achieved and in those atlantoaxial subluxations that were irreducible an intraoperative reduction was done.
Materials and Methods:
A retrospective evaluation of 53 cases of odontoid fractures treated over a 9-year period is being reported. All odontoid fractures without AA instability (n=29) were initially managed conservatively. Three patients who did not achieve union with conservative management were treated with delayed anterior screw fixation. Twenty-four cases of odontoid fractures were associated with AA instability; 17 of them could be reduced with skeletal traction and were managed with posterior fusion and fixation. Of the seven cases that were irreducible, the initial three cases were treated by odontoid excision followed by posterior fusion and fixation; however, in the later four cases, intra operative reduction was achieved by a manipulation procedure, and posterior fusion and fixation was performed.
Results:
Twenty-six of 29 cases of odontoid fracture without AA instability achieved fracture union with conservative management whereas the remaining three patients achieved union following delayed anterior odontoid screw fixation. 17 out of 24 odontoid fracture with atlantoaxial dislocation could be reduced on traction and these patients underwent posterior fusion and fixation. Optimal or near optimal reduction was achieved by on table manipulation in four cases which were irreducible with skeletal traction. Atlantoaxial stability was achieved in all cases. All cases were noted to be stable on evaluation with x-rays at six months.
Conclusions:
The initial conservative management and use of odontoid screw fixation only in cases where conservative management for 6-12 weeks has failed to provide fracture union have shown good outcome in type II odontoid fracture without AA instability rates. Intraoperative manipulation and reduction in patients where AA subluxation failed to reduce on skeletal traction followed by posterior fusion obviates the need for transoral odontoid excision.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,200
277
5
CASE REPORTS
Nonsecretory multiple myeloma
Seshikanth Middela, Prakash Kanse
October-December 2009, 43(4):408-411
DOI
:10.4103/0019-5413.55979
PMID
:19838394
Multiple myeloma is characterized by clonal proliferation of plasma cells usually of the B cell type.The skeletal manifestations are usually osteolytic lesions whose differential diagnosis includes primary and secondary bone tumor. This tumor is characterized by the presence of abnormal paraprotein 8 in blood and urine. However, one to five per cent of the cases do not have any protein. Hence they are termed nonsecretory. It often poses a diagnostic dilemma when it is presented to orthopedic surgeons with no clear features of the disease. Our case report exemplifies such a diagnostic dilemma. A high index of suspicion must be borne in mind when excluding multiple myeloma as a cause of pain, pathological fracture or lytic lesion.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,059
305
6
Spontaneous subdural hematoma of the thoracolumbar region with massive recurrent bleed
Rafael Cincu, Francisco de Asis Lorente, David Rivero, Jose Eiras, Jose Ramon Ara
October-December 2009, 43(4):412-415
DOI
:10.4103/0019-5413.49383
PMID
:19838395
Spinal subdural hematoma is a rare disorder and can be caused by abnormalities of coagulation, blood dyscrasias, lumbar puncture, trauma, underlying neoplasm, and arteriovenous malformation. We discuss an unusual case of an elderly woman who presented with spontaneous spinal subdural hematoma and developed massive rebleeding on the third day following initial evacuation of hematoma. This case illustrates that a patient with routine normal coagulation profile and adequate hemostasis can still harbor platelet dysfunction (in present case due to polycythemia) and later on can manifest as rebleeding and neurological deterioration.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,707
180
6
ORIGINAL ARTICLES
Correlation of the SLAP lesion with lesions of the medial sheath of the biceps tendon and intra-articular subscapularis tendon
William F Bennett
October-December 2009, 43(4):342-346
DOI
:10.4103/0019-5413.55974
PMID
:19838383
Background:
Superior labral anterior to posterior (SLAP) lesions have been well described in the literature and are thought to be secondary to traction injuries to the biceps anchor and/or falls on the outstretched arm. The pulley has recently been described as a structure that aids in the prevention of biceps instability. The intra-articular subscapularis insertion (IASS) has been noted to contribute to the robust nature of the medial sheath. The purpose of the study was to determine a potential correlation of SLAP lesions and pulley lesions with/without IASS lesions, (hereafter referred to as medial sheath) as forces that can disrupt the biceps anchor and may also disrupt structures of the medial sheath or vice-versa.
Materials and Methods:
Three hundred and sixteen consecutive shoulder arthroscopies performed by one surgeon were reviewed retrospectively. Operative reports and arthroscopic pictures were carefully reviewed with particular attention paid to the labral and pulley pathology. Selection bias was noted as the author had never operated primarily for a Type 1 SLAP lesion. Following, however, and as such, the exclusion criteria, was a Type 1 SLAP.
Results:
There were a total of 30 SLAP lesions and a total of 126 medial sheath lesions. There were 13 patients who had both SLAP and medial sheath lesions. There were 17 patients who had a SLAP lesion without a medial sheath lesion. There were 96 medial sheath lesions without a SLAP. A comparison of rates between patients who had a medial sheath lesion with a SLAP and those who had a medial sheath lesion without a SLAP, for the 316 patients, and when tested with a Fisher exact test revealed that there was no statistical significance,
P
= 0.673. The prevalence of SLAP lesions in this population of 316 patients was 9.4%, Buford 1%, medial sheath lesions 39%, and SLAP and medial sheath lesions 4%. Interestingly, there were three Buford complexes, all associated with a SLAP and one Buford complex was associated with both a SLAP and a pulley. When looking at the rate for medial sheath lesions when restricted to patients with SLAP lesions, the medial sheath lesion rate was 43.3% (13/30; 95% confidence interval 19.6-66.9%). The medial sheath lesion rate for patients with SLAP lesions differs from a rate of zero and is statistically significant, with a
P0 value
<0.05. In other words, when a SLAP lesion is present there is a statistically significant rate of medial sheath lesions, a previously unpublished association.
Conclusions:
With a 43% association of the medial sheath lesion with SLAP lesions, the author postulates that forces that affect the biceps anchor may also damage the pulley system of the bicipital sheath and, as such, this anatomic structure should be evaluated, especially when SLAP lesions are present.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,602
250
14
Metacarpal lengthening by distraction histiogenesis in adults
Sakti Prasad Das, Ram Narayan Mohanty, Sanjay Kumar Das
October-December 2009, 43(4):379-382
DOI
:10.4103/0019-5413.55467
PMID
:19838389
Background:
Metacarpal lengthening in the hand is a new application for distraction neo-histiogenesis. Metacarpal lengthening with distraction helps in improvement in pinch function. Thumb lengthening is technically easy in comparison to other metacarpals. We present the operative treatment and post-operative outcome in nine patients with amputations and congenital anomalies.
Materials and Methods:
Nine patients underwent distraction osteogenesis for the treatment of amputations of the hand and other congenital anomalies. The dominant right hand was operated in eight cases and the left hand in one case. There were six males and three females. Improvement of function was always the aim of surgery. Age range was between 18 and 23 years. Thumb lengthening was performed in five patients and that of the index finger in four patients. Distraction started on the fifth post-operative day at the rate of 0.25 mm/day. Sensory function and bone consolidation was assessed before fixator removal.
Results:
The mean duration of distraction was 51 days (range, 42-60 days) and the distractor was removed at a mean of 150 days (range, 140 and 160 days) and the bones were lengthened by a mean of 24 mm (range, 20-28 mm) There was improvement of function in all cases.
Conclusion:
The metacarpal lengthening by distraction histiogenesis in congenital and traumatic amputations is safe and simple method to improve pinch function of hand.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,294
225
4
Effect of amino acids lysine and arginine on fracture healing in rabbits: A radiological and histomorphological analysis
Shivam Sinha, Satish Chandra Goel
October-December 2009, 43(4):328-334
DOI
:10.4103/0019-5413.55972
PMID
:19838381
Background:
Amino acids like arginine and lysine have been suggested to hasten the process of fracture healing by improving the local blood supply, supplementing growth factors, and improving collagen synthesis. We studied the role of lysine and arginine in the fracture repair process with regard to the rate of healing, probable mechanisms involved in the process, and mutual synergism between these agents.
Materials and Methods:
In an experimental study, 40 rabbits were subjected to ulnar osteotomy. They were distributed in control (14) and test groups (26). Twenty-six animals in the test group were fed with a diet rich in lysine and arginine. Both the groups were followed radiologically and histologically till union.
Results:
There was better healing of osteotomy in terms of better vascularization, callus formation, and mineralization in the test group. The time of healing in the test group was reduced by a period of 2 weeks.
Conclusion:
We conclude that amino acids like arginine and lysine may hasten fracture healing.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,278
234
5
Limb conservation in extremity soft tissue sarcomas with vascular involvement
Rajaraman Ramamurthy, Jagadish Chandra Bose Soundrarajan, Viswanathan Mettupalayam, Subbiah Shanmugham, Balasubramanian Arumugam, Saravanan Periasamy
October-December 2009, 43(4):403-407
DOI
:10.4103/0019-5413.54969
PMID
:19838393
Background:
The major neurovascular involvement and large primary tumors are indication of amputation. The present study is an attempt to explore the feasibility of a limb salvage surgery in extremity sarcoma cases with major vessel involvement. Oncological outcomes and surgery-related morbidities are compared with those reported in literature.
Materials and Methods:
A retrospective review of all limb salvage surgeries done in our department between 2005 and 2008 was done and four cases of extremity sarcoma of lower limb involving femoral vessels analyzed. Interpretation of data from these cases, along with review of literature, is done.
Results:
In all these cases a wide monobloc excision was done adhering to oncological principles. This required resection of superficial femoral artery alone in two cases, resection of superficial femoral artery along with common femoral vein and femoral nerve in another, and of common femoral vein alone in yet another. Reconstruction was done in all these cases with reversed long saphenous vein graft. Histopathology of resected margins was free of tumor in all the four patients. One patient developed local recurrence and one developed distant metastsis. Two were disease free for one year with good functional limb, one has been disease-free for three years and another was disease-free at two years, after which he defaulted further follow-up. One patient developed arterial blowout which required ligation of common femoral artery which resulted in gangrene of the limb. He underwent amputation.
Conclusion:
Major neurovascular involvement in extremity sarcoma is not considered a contraindication for limb salvage surgery. Review of literature also supports our view. Post-operative wound related complications are more in this group of patients. However, long term functional outcome is good. Literature suggests a good long term local control after vascular resection and reconstruction.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
2,944
216
4
Hip arthrodesis in children: A review of 28 patients
Ashok K Banskota, Shikshya P Shrestha, Bibek Banskota, Binod Bijukacche, Tarun Rajbhandari
October-December 2009, 43(4):383-388
DOI
:10.4103/0019-5413.55977
PMID
:19838390
Background:
The best method of treating intractable hip pain in an unsalvageable hip joint in a child is still a subject open to debate. We believe that hip arthrodesis in such patients provides a painless and stable hip for most activities of daily living in our challenging rural terrain. Therefore, we conducted this study to assess the functional ability of children with painful hip arthrosis treated by arthrodesis of the hip.
Materials and Methods:
A retrospective evaluation of 28 children (out of 35) who had an arthrodesis of the hip performed between 1994 and 2008 was carried out. The average age was 14 years, with 12 males and 16 females. There was involvement of the right hip in 13 and left in 15 cases. The average duration of follow-up was 4.87 years. The preferred position of the hip for arthrodesis was 20-30° of flexion, neutral abduction-adduction, and neutral rotation, irrespective of the method of fixation.
Results:
The average duration of clinical and radiological arthrodesis was found to be 4 months (2-6 months). At the last follow-up, all patients were painfree and had good ambulatory capacity. The average Modified Harris Hip Score increased from 53 to 84 and the average post-surgical limb length discrepancy was 1.3 cm, which was well tolerated in all cases. Patients, however, had difficulty in squatting and had to modify their posture for foot care, putting on shoes, etc. Also, some patients complained of ipsilateral knee, contralateral hip, or low back pain with prolonged activity, but this was not severe enough to restrict activity except in one case that was known to have juvenile rheumatoid arthritis and needed ambulatory aid.
Conclusion:
In an environment where pathology generally presents very late and often in a dramatic manner, where the patient's socioeconomic status, understanding, compliance, and the logistics of follow-up are consistently a challenge in management, hip arthrodesis has been an important procedure for our patient group, with good short-term results and promising midterm, and, hopefully, long-term prospects. In our series of patients, we have been successful in restoring painfree mobility.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
2,869
261
6
Transplantation of free tibial periosteal grafts for the repair of articular cartilage defect: An experimental study
Ravijot Singh, Vijendra Chauhan, Neena Chauhan, Sansar Sharma
October-December 2009, 43(4):335-341
DOI
:10.4103/0019-5413.55973
PMID
:19838382
Background:
Articular chondrocytes have got a long lifespan but rarely divides after maturity. Thus, an articular cartilage has a limited capacity for repair. Periosteal grafts have chondrogenic potential and have been used to repair defects in the articular cartilage. The purpose of the present study is to investigate the differentiation of free periosteal grafts in the patellofemoral joint where the cambium layer faces the subchondral bone and to investigate the applicability of periosteal grafts in the reconstruction of articular surfaces.
Materials and Methods:
The study was carried out over a period of 1 year on 25 adult, male Indian rabbits after obtaining permission from the institutional animal ethical committee. A full-thickness osteochondral defect was created by shaving off the whole articular cartilage of the patella of the left knee. The defect thus created was grafted with free periosteal graft. The patella of the right knee was taken as a control where no grafting was done after shaving off the articular cartilage. The first animal was used to study the normal histology of the patellar articular cartilage and periosteum obtained from the medial surface of tibial condyle. Rest 24 animals were subjected to patellectomy, 4 each at serial intervals of 2, 4, 8, 16, 32 and 48 weeks and the patellar articular surfaces were examined macroscopically and histologically.
Results:
The grafts got adherent to the underlying patellar articular surface at the end of 4 weeks. Microscopically, graft incorporation could be appreciated at 4 weeks. Mesenchymal cells of the cambium layer were seen differentiating into chondrocytes by the end of 4 weeks in four grafts (100%) and they were arranged in a haphazard manner. Till the end of 8 weeks, the cellular arrangement was mostly wooly. At 16 weeks, one graft (25%) had wooly arrangement of chondrocytes and three grafts (75%) had columnar formation of cells. Same percentage was maintained at 32 weeks. Four grafts (100%) at 48 weeks showed columnar orientation. The control side showed no changes over the shaved off articular surface in all the rabbits. One rabbit at 4 weeks had a dislocation of the patella on the control side. None of the rabbits developed any infection or wound dehiscence.
Conclusion:
Autologous periosteal graft transplantation can be a promising substitute for articular cartilaginous defects.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
2,748
225
2
CASE REPORTS
Direct bony invasion of malignant melanoma
Viswanath Mula, Adhip Mandal, Edward Britton, Vaidyanathan Shiv Shanker
October-December 2009, 43(4):420-423
DOI
:10.4103/0019-5413.55469
PMID
:19838397
Malignant melanoma is known to spread by local extention, by the lymphatics by the blood stream. Direct invasion of the bone from a cutaneous melanoma is unknown. Hence, this case is presented in view of its rarity. A 75-year-old Caucasian lady presented with a small papillary lesion in the region of a recurrent chronic cellulitis on the lower third of the lateral aspect of the right leg. Histopathology diagnosed the lesion as locally advanced malignant melanoma. Radiological investigations by X-ray and magnetic resonance imaging revealed malignant infiltration of the tibia in its mid and lower third with two soft tissue metastatic masses adjacent. Histology following amputation confirmed malignant melanoma with cranial resection margin involvement. She underwent a further above-knee amputation followed by chemotherapy. The patient recovered from the amputation but subsequently died 6 months later due to bronchopneumonia from lung metastasis.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
2,613
161
2
EDITORIAL
Research in orthopedics: A necessity
Anil K Jain
October-December 2009, 43(4):315-317
DOI
:10.4103/0019-5413.55968
PMID
:19838377
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
1,929
468
2
CASE REPORTS
Late arthroscopic retrieval of a bullet from hip joint
Ravi K Gupta, Varun Aggarwal
October-December 2009, 43(4):416-419
DOI
:10.4103/0019-5413.54764
PMID
:19838396
We describe a case of arthroscopic retrieval of a bullet from the hip joint of an 18-year-old boy, who sustained the injury four months back, accidentally, while bird hunting with a country made shotgun. The surgery was performed with the standard ordinary instrumentation of knee arthroscopy. The patient became pain-free the same evening and started partial weight bearing on the next day of surgery. At 13 months follow-up, the patient had returned to normal activity without any functional limitations.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
2,258
131
5
PERSPECTIVES
Basic research in orthopedics: South Africa
Shunmugam Govender
October-December 2009, 43(4):324-325
DOI
:10.4103/0019-5413.55970
PMID
:19838379
[FULL TEXT]
[PDF]
[PubMed]
1,976
359
-
ORIGINAL ARTICLES
Clinical and radiological instability following standard fenestration discectomy
Amrithlal A Mascarenhas, Issac Thomas, Gaurav Sharma, Joe Joseph Cherian
October-December 2009, 43(4):347-351
DOI
:10.4103/0019-5413.55465
PMID
:19838384
[FULL TEXT]
[CITATIONS]
[PubMed]
2,082
215
3
PERSPECTIVES
Basic research in orthopedics: India
Satish Chandra Goel
October-December 2009, 43(4):326-327
DOI
:10.4103/0019-5413.55971
PMID
:19838380
[FULL TEXT]
[PDF]
[PubMed]
1,781
232
-
LETTERS TO EDITOR
Vertebroplasty for osteoporotic vertebral fractures: Additional concern on its usefulness
Viroj Wiwanitkit
October-December 2009, 43(4):424-424
DOI
:10.4103/0019-5413.55980
PMID
:19838398
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
1,509
174
1
Author's reply
Peter Diel, Dominique Merky, Christoph Roder, Albrecht Popp, Malgorzata Perler, Paul Ferdinand Heini
October-December 2009, 43(4):424-424
PMID
:19838399
[FULL TEXT]
[PDF]
[PubMed]
1,544
96
-
Advertise
Addresses
Most Popular Articles
My Preferences
Contact us
|
Sitemap
|
Advertise
|
What's New
|
Feedback
|
Copyright and Disclaimer
|
Publication ethics and publication malpractice statement
© Indian Journal of Orthopaedics | Published by Wolters Kluwer -
Medknow
Online since 9
th
November, 2006