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| REVIEW ARTICLE |
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Tourniquets in orthopedic surgery  |
p. 377 |
Jai Prakash Sharma, Rashmi Salhotra DOI:10.4103/0019-5413.98824 PMID:22912509Tourniquets are commonly used in limb surgeries, be it orthopedic or plastic surgeries. But the inflation pressures, the duration, and release guidelines are still not clear. According to a survey, majority of orthopedic surgeons inflate the tourniquet to fixed pressures for the upper and the lower limbs without considering the baseline blood pressure of the patient on whom the tourniquets are being applied. This review was designed to recall and review the safe use of tourniquets and the various techniques that can be employed to minimize the complications of tourniquet use. Google, science direct, and pubmed were searched for appropriate literature and relevant articles were identified. |
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| ORIGINAL ARTICLES |
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Monitoring of fracture healing by electrical conduction: A new diagnostic procedure |
p. 384 |
Shanmugasundaram Kumaravel, S Sundaram DOI:10.4103/0019-5413.97260 PMID:22912510Background: Electrical stimulation of fractures has been reported to enhance fracture healing. X-rays are normally used to assess union of fractures. Electrical conduction is not tried as a tool to study fracture healing. The current study focuses on electrical conduction as a diagnostic tool to assess fracture healing and new bone formation. The aim was to find if electrical resistance across the fracture can be used as a tool to study fracture healing which can be verified with simultaneous radiographs.
Materials and Methods: A prospective study was conducted where 12 open fractures of tibia, including two with bone defects were evaluated. They were debrided and four-carbon ring Ilizarov external fixators were applied. Their healing was followed with clinical assessment and periodical X-rays till the endpoint of fracture union and then the rings were removed. In addition, all these cases also had application of electrical voltage in the range of 0.1-1.0 V DC in 0.1 V increments, across the two wires on either side of fracture. The output current was recorded by an ammeter connected in series. Resistance calculated for various voltages was plotted as a graph for the period of fracture treatment and the characteristics were studied. This graph was compared with the appearance of new bone in the X-rays.
Results: In all cases, when the above graph stabilized, in the consecutive recordings, the X-rays showed healing (bridging callus) matching the curve and the patient was able to load the limb. The time of stabilization of this graph for a specific voltage was different in individual cases. However, for a given case, the resistance characteristics were the same for the entire voltage range of 0.1-1.0 V.
Conclusion: If the resistance versus day curve stabilizes on the consecutive recordings, we can predict that the fracture is in the process of healing. This stabilization period also matched the patients' ability to comfortably load the limb and also the radiographs which showed bridging callus (healing). If this is used as a positive criterion for fracture healing in future, the radiation exposure by X-rays shall be less. |
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Effects of immobilization on thickness of superficial zone of articular cartilage of patella in rats |
p. 391 |
Khadija Iqbal, Yunus Khan, Liaquat Ali Minhas DOI:10.4103/0019-5413.98826 PMID:22912512Background: Articular cartilage normally functions as a load-bearing resistant material in joints. Patella is composed of hyaline cartilage and spongy bone. Chondrocytes form only 1-5% volume of the articular cartilage. They receive their nutrition by diffusion through the matrix. The alteration in articular cartilage become apparent following immobilization, from 4 to 6 weeks. Until now, focus of research has been the whole cartilage. Zonal changes have not been studied in detail. Since superficial zone bears maximum load and is the first zone to come in contact, the present study was designed to determine changes in thickness on immobilization and remobilization in superficial zone after dividing it into proximal, central, and distal segments.
Materials and Methods: Forty male rats belonging to Sprague Dawley strain were divided into two groups. Group 1 (n=20) subdivided into an experimental subgroup of 10 rats that were immobilized in plaster of Paris (POP) for 4 weeks and a control subgroup of 10 that were not immobilized. Group 2 (n=20) subdivided into an experimental subgroup of 10 rats that were immobilized for 4 weeks and remobilized for next 4 weeks and a control subgroup of 10 animals that were not immobilized. At the end of the experimental period, the knee joint was dissected and was cut in sagittal plane. The section was fixed in 10% formalin for 48 hours. Specimen was decalcified using ethylenediaminetetraacetic acid (EDTA). The paraffin blocks of 7 μm sections were cut and stained by H and E stain for routine histology and Alcian blue stain and Mallory Trichrome for fine structural microscopy. The zones were named as superficial transitional, radial, and hypertrophic according to the shape of cells present in each zone. The superficial zone was divided into superior part, central, and inferior parts. These parts were labeled as central, proximal, and distal segments. The calibrated stage micrometer was used to calibrate the ocular micrometer under objectives of different power. The ocular micrometer was placed inside the ocular lens. It was calibrated with the stage micrometer under objective lenses of different power. The number of divisions of ocular covering each zone was calculated. These divisions were converted into micrometer and the actual thickness was calculated.
Results: The significant decrease in thickness of superficial zone in proximal, central and distal segment was observed in experimental group in comparison to control group. When the experimental subgroup of group 2 was compared with experimental subgroup of group 1 (group immobilized for 4 weeks), no significant reversal was seen in superficial zone and instead significant decrease was observed in distal segment. Fibrous connective tissue was increased adjacent to superficial zone.
Conclusion: Each segment of superficial zone behaves differentially on immobilization and remobilization. Perhaps a much longer duration of remobilization is required to reverse changes of immobilization in articular cartilage and plays a significant role in knee joint movements. |
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Biomechanical efficacy of monoaxial or polyaxial pedicle screw and additional screw insertion at the level of fracture, in lumbar burst fracture: An experimental study |
p. 395 |
Hongwei Wang, Changqing Li, Tao Liu, Wei-dong Zhao, Yue Zhou DOI:10.4103/0019-5413.98827 PMID:22912513Background: Use of a pedicle screw at the level of fracture, also known as an intermediate screw, has been shown to improve clinical results in managing lumbar fracture, but there is a paucity of biomechanical studies to support the claim. The aim of this study was to evaluate the effect of adding intermediate pedicle screws at the level of a fracture on the stiffness of a short-segment pedicle fixation using monoaxial or polyaxial screws and to compare the strength of monoaxial and polyaxial screws in the calf spine fracture model.
Materials and Methods: Flexibility of 12 fresh-frozen calf lumbar spine specimens was evaluated in all planes. An unstable burst fracture model was created at the level of L3 by the pre-injury and dropped-mass technique. The specimens were randomly divided into monoaxial pedicle screw (MPS) and polyaxial pedicle screw (PPS) groups. Flexibility was retested without and with intermediate screws (MPSi and PPSi) placed at the level of fracture in addition to standard screws placed at L2 and L4.
Results: The addition of intermediate screws significantly increased the stability of the constructs, as measured by a decreased range of motion (ROM) in flexion, extension, and lateral bending in both MPS and PPS groups (P < 0.05). There was neither any significant difference in the ROM in the spines of the two groups before injury, nor a difference in the ROM between the MPSi and PPSi groups (P > 0.05), but there was a significant difference between MPS and PPS in flexion and extension in the short-segment fixation group (P < 0.05).
Conclusions: The addition of intermediate screws at the level of a burst fracture significantly increased the stability of short-segment pedicle screw fixation in both the MPS and PPS groups. However, in short-segment fixation group, monoaxial pedicle screw exhibited more stability in flexion and extension than the polyaxial pedicle screw. |
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Chondrocyte source for cartilage regeneration in an immature animal: Is iliac apophysis a good alternative? |
p. 402 |
Karthikeyan Rajagopal, Vivek Dutt, A Soosai Manickam, Vrisha Madhuri DOI:10.4103/0019-5413.98828 PMID:22912514Background: Autologous articular cartilage at present forms the main source of chondrocytes for cartilage tissue engineering. In children, iliac apophysis is a rich and readily accessible source of chondrocytes. This study compares the growth characteristics and phenotype maintenance of goat iliac apophysis growth plate chondrocytes with those sourced from goat articular cartilage, and thereby assesses their suitability for autologous chondrocyte transplantation in immature animals for growth plate and articular cartilage regeneration.
Materials and Methods: Four sets of experiments were carried out. Cartilage samples were harvested under aseptic conditions from goat iliac apophysis and knee articular cartilage. The chondrocytes were isolated in each set and viable cells were counted and subsequently cultured as a monolayer in tissue culture flasks containing chondrogenic media at 2.5 × 10 3 cells/cm 2 . The growth was periodically assessed with phase contrast microcopy and the cells were harvested on 8 th and 15 th days for morphology, cell yield, and phenotype assessment. Student's t-test was used for comparison of the means.
Results: Confluence was reached in the iliac apophysis growth plate chondrocytes flasks on the 10 th day and the articular cartilage chondrocytes flasks on the 14 th day. Mean cell count of growth plate chondrocytes on the 8 th day was 3.64 × 10 5 (SD = 0.601) and that of articular cartilage chondrocytes was 1.40 × 10 5 (SD = 0.758) per flask. The difference in the means was statistically significant (P = 0.003). On the 15 th day, the mean cell number had increased to 1.35 × 10 6 (SD = 0.20) and 1.19 x 10 6 (SD = 0.064) per flask, respectively. This difference was not statistically significant (P = 0.26). The population doubling time on the 8 th day of cell culture was 3.18 and 6.24 days respectively, for iliac apophyseal and articular cartilage chondrocytes, which was altered to 3.59 and 3.1 days, respectively, on the 15 th day. The immunocytochemistry showed 100% retention of collagen 2 positive and collagen 1 negative cells in both sets of cultures in all samples.
Conclusion: Iliac apophysis is a rich source of chondrocytes with a high growth rate and ability to retain phenotype when compared to articular cartilage derived chondrocytes. Further in vivo studies may determine the efficacy of physeal and articular repair in children with apophyseal chondrocytes. |
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Enhanced recovery program in total hip arthroplasty |
p. 407 |
Amitabh J Dwyer, Payam Tarassoli, William Thomas, Paul Porter DOI:10.4103/0019-5413.98829 PMID:22912515Background: Enhanced recovery program (ERP) was implemented to optimize the hospital stay in total hip arthroplasty. This study assessed the effects of optimizing preoperative and perioperative care using enhanced recovery (ER) on patients undergoing Total hip arthroplasty.
Materials and Methods: We compared a prospective group of 64 patients on the ER program with a historic cohort of 63 patients that received conventional care (non ER).
Results: ER patients were discharged earliest from hospital [mean length of stay (LOS) 5.3 days, median 4; P < 0.001] as compared to a mean of 8.3 days among non ER patients. Comparison based on American Association of Anesthesiologists (ASA) grades, preoperative hemoglobin, and body mass index (BMI) revealed that patients with ASA grade 3, preoperative hemoglobin of <14 g/dl, and BMI >30 on ER program spent shorter time in hospital as compared to the non ER's conventionally treated patients with more favorable physiological parameters of ASA grade 1 and 2, preoperative hemoglobin of >14 g/dl, and BMI <30.
Conclusion: The ER protocol is universally beneficial and confers an advantage regardless of the patients' preoperative condition. |
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Thrombotic risk assessment questionary helps increase the use of thromboprophylaxis for patients with pelvic and acetabular fractures |
p. 413 |
Haili Wang, Wei Chen, Yanling Su, ZhiYong Li, Ming Li, Zhanpo Wu, Yingze Zhang DOI:10.4103/0019-5413.98830 PMID:22912516Background: Pelvic and acetabular fractures have been known as one of the high risk factors for developing deep vein thrombosis (DVT), but thromboprophylaxis for patients with such fractures remains underused despite its widely accepted benefits. Current guidelines have not been universally adopted in clinical practice. The purpose of this study is to introduce a Thrombotic Risk Assessment Questionary (assessment table) according to evidence-based guidelines and evaluate its impact on the use of thromboprophylaxis for patients with pelvic and acetabular fractures.
Materials and Methods: We retrospectively reviewed 305 consecutive patients with pelvic and acetabular fractures from August 1, 2008 through September 30, 2010. The control group without using the assessment table included 153 patients admitted during the first 13 months, and the assessment group using the assessment table included 152 patients admitted during the following months. Data on clinical outcomes of DVT, the number of patients receiving prophylaxis, and the time of the first dose of anticoagulant were collected.
Results: Compared with the control group, Patients using the assessment table were more likely to be given DVT prophylaxis (84.2% vs. 37.3%, P < 0.05) and the time of the first dose of anticoagulant was reduced (4.32 days ± 4.78 days vs. 6.6 days ± 5.96 days, P < 0.05). Patients in the assessment group had lower risk of developing DVT (8.6% vs. 20.3%, P < 0.05).
Conclusion: The assessment table can significantly improve the use of thromboprophylaxis after pelvic and acetabular fractures, which will likely reduce the incidence of DVT. Developing individual hospital prophylaxis strategy is an effective way to determine whether hospitalized patients should receive pharmacologic and/or mechanical prophylaxis or not. |
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Association between single nucleotide polymorphism in collagen IX and intervertebral disc disease in the Indian population |
p. 420 |
Tushar N Rathod, Ajay S Chandanwale, Shubhangi Gujrathi, Vinayak Patil, Shital A Chavan, Munjal N Shah DOI:10.4103/0019-5413.97261 PMID:22912517Background: Symptomatic intervertebral disc degeneration is being recently reported in younger population, questions the basis of its degenerative etiology. Latest evidences show that genetics play a significant role. Collagen IX, an important constituent of disc, is found to be altered in genetically predisposed individuals. Mutations have been reported in COL9A2 and COL9A3 genes, which encode Collagen IX, in Finnish and various other populations. The purpose of the present study is to test the significance of these genes in the Indian population.
Materials and Methods: One hundred proven cases of intervertebral disc disease (IDD) of various regions of spine were selected for the study, along with matched controls. They were tested for the above mentioned alleles by allelic discrimination method with real-time polymerase chain reaction (PCR) study after isolation of DNA from blood sample. Each blood sample was classified into one of the three types - homozygous, heterozygous, and wild (normal) type allele - separately for COL9A2 and COL9A3 genes.
Results: Homozygosity for COL9A2 allelic variation was associated with 100% occurrence of the disease. Heterozygous allele of COL9A2 was significantly higher in the study group (42%) as compared to the control group (17%). In contrast, allelic variation in COL9A3 gene was found to have no significant correlation with disc disease. There was no single patient with homozygous allelic variation for COL9A3, suggesting predominance of COL9A2 variation in the Indian population.
Conclusion: This candidate gene strategy approach adds considerably to our knowledge of genetic makeup of Indian populations in relation with disc disease. This study highlights importance of COL9A2 gene variation especially of homozygous variety in contrast to COL9A3 variation in causing disc disease in Indian population. |
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Postoperative discitis following single-level lumbar discectomy: Our experience of 17 cases |
p. 427 |
Saumyajit Basu, Jay Deep Ghosh, Farid H Malik, Agnivesh Tikoo DOI:10.4103/0019-5413.98831 PMID:22912518Background: The established protocols of treatment of postoperative lumbar discitis have not been validated till date. We report a retrospective analysis of a series of patients with discitis following single level lumbar discectomy. We analyzed the outcome of conservative treatment of postoperative discitis with the objective to define when and what surgery was required when the conservative treatment failed.
Materials and Methods: A total of 17 cases of postoperative discitis treated from 2002 to 2009 were followed up and evaluated clinically, radiologically and by laboratory investigations. All the patients were treated initially conservatively with rest and antibiotic therapy after diagnosis and those who did not respond to conservative treatment of at least 4 weeks were treated surgically. The cases were followed up with serial C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), X-ray, computed tomography (CT) scan and magnetic resonance imaging (MRI) for at least 1 year.
Results: The mean followup was 40.38 months (range 12-86 months). Four cases failed to respond to conservative therapy and were treated surgically. In three of these four cases, open debridement, transpedicular fixation and posterolateral fusion was performed, and in the fourth case percutaneous transpedicular fixation was done. In the former group, one case was diagnosed to be tubercular, in another case Staphylococcus aureus was cultured where as the third case culture was sterile. All operated patients showed evidence of interbody fusion at 1 year followup.
Conclusions: Early detection and aggressive treatment are paramount in managing postoperative discitis and the majority do well with conservative treatment. Surgical management in the form of transpedicular fixation and debridement, when required, gives excellent results. |
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Lumbar pedicle screw placement: Using only AP plane imaging |
p. 434 |
Anil Sethi, Adrienne Lee, Rahul Vaidya DOI:10.4103/0019-5413.98832 PMID:22912519Background: Variations in the pedicle morphology and presence of spinal deformities can make pedicle screw placement challenging. Recently, computerized tomography (CT) guided screw placement has reportedly improved the surgical accuracy of pedicle screw insertion. However, it is time consuming and expensive. We combined single-plane fluoroscopy in AP projection alone with tactile guidance for placing pedicle screws more efficiently and accurately. This report presents our results with this technique.
Materials and Methods: An Institutional Review Board (IRB) approved retrospective study was carried out on 308 patients who underwent lumbar spinal fusion with 1806 pedicle screws placed using fluoroscopy only in the AP plane. There were 182 patients with two-level fusion, 79 with single-level fusion, 26 with three-level fusion, and 21 with more than three-level fusions. The indications of surgery included spondylolisthesis, adult scoliosis, revision surgery, lumbar canal stenosis, and discogenic pain. Pedicle screws were inserted under fluoroscopic guidance in the AP plane alone with a final lateral image after completion of implant placement. Radiographs were performed postoperatively in all patients and CT scans were obtained on 78 patients with 588 screws.
Results: Twenty nine (5%) cortical wall perforations were noted amongst the 588 screws that were evaluated with a CT scan and did not result in postoperative vascular or neural complications. Anterior cortical vertebral violation was noted in 14 patients, while in 9 patients the screws penetrated the lateral wall of the pedicle. The medial wall of the pedicle was encroached in six patients with no frank perforations.
Conclusion: Placement of pedicle screws under fluoroscopic guidance using AP plane imaging alone with tactile guidance is safe, fast, and reliable. However, a good understanding of the radiographic landmarks is a prerequisite. |
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Augmented osteosynthesis with tensor fascia latae muscle pedicle bone grafting in neglected femoral neck fracture  |
p. 439 |
Basant Kumar Bhuyan DOI:10.4103/0019-5413.97263 PMID:22912520Background: Neglected intracapsular femoral neck fracture in young patients may fail to unite because of the excessive shearing strain at the fracture site and it is a surgical challenge to any orthopedic surgeon. The problem is compounded by resorption of the femoral neck and avascular necrosis (AVN) of femoral head. There is no satisfactory solution available in the management of femoral neck fracture as far as the union of the fracture and AVN of femoral head are concerned. Muscle pedicle bone grafting has been advocated to provide additional blood supply to the femoral head. We report a retrospective analysis of 48 cases of neglected femoral neck fracture treated by internal fixation and tensor fascia latae based muscle pedicle bone grafting.
Materials and Methods: 48 patients with femoral neck fractures with age varied from 20 to 53 years (average age 32.9 years) with male to female ratio of 2:1 were enrolled. All fractures were more than 3 weeks old with mean delay being 86 days (22-150 days). Open reduction and internal fixation along with tensor fascia latae muscle pedicle bone grafting was done in all cases. It was supplemented by multiple drilling and cortico-cancellous bone grafting. Fracture fixation was done with three parallel 6.5-mm AO cannulated cancellous lag screws and the graft fixed with a 4-mm cancellous screw to provide a secure fixation. During the followup period of 2-6.8 years (average 4.4 years) the results were assessed clinically by modified Harris hip scoring system and radiologically by the evidence of signs of fracture union.
Results: Union was achieved in 41/48 (85.41%) cases which were followed for an average period of 4.4 years (2-6.8 years) with good functional results and ability to squat and sit cross-legged. Results were assessed according to modified Harris Hip Scoring system and found to be excellent in 19, good in 22, fair in 5, and poor in 2 patients. Complications were nonunion, (n=3) avascular necrosis (n=2), and coxa vara deformity (n=2).
Conclusion: Internal fixation with muscle pedicle bone grafting is a suitable option to secure union in neglected femoral neck fractures in physiologically active patients with late presentation. |
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Reconstruction of medial patellofemoral ligament for chronic patellar instability |
p. 447 |
K Raghuveer Reddy, Chandra Bdr Mishra DOI:10.4103/0019-5413.97259 PMID:22912521Background: Disruption of the capsule, medial patellar retinaculum, and/or vastus medialis obliqus has been associated with recurrent patellar instability. Biomechanical studies have shown that the medial patellofemoral ligament (MPFL) is the main restraint against lateral patella displacement and reconstruction of the MPFL has become an accepted surgical technique to restore patellofemoral stability in patients having recurrent patellar dislocation. We report a prospective series of patients of chronic patellar instability treated by reconstruction of medial patellofemoral ligament.
Materials and Methods: Twelve patients (15 knees) with recurrent dislocation of patella, were operated between January 2006 and December 2008. All patients had generalised ligament laxity with none had severe grade of patella alta or trochlear dysplasia. The MPFL was reconstructed with doubled semitendinosus tendon. Patients were followed up with subjective criteria, patellar inclination angle, and Kujala score.
Results: The mean duration of followup after the operative procedures was an average of 42 months (range 24-60 months) . 10 knees showed excellent results, 3 knees gave good results, and 2 knees had a fair result. The average patellar inclination angle decreased from 34.3° to 18.6°. The average preoperative Kujala functional score was 44.8 and the average postoperative score was 91.9.
Conclusion: MPFL reconstruction using the semitendinosus tendon gives good results in patients with chronic patellar instability without predisposing factors like severe patella alta and high-grade trochlear dysplasia, and for revision cases. |
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A retrospective analysis of medial opening wedge high tibial osteotomy for varus osteoarthritic knee |
p. 455 |
Chaturong Pornrattanamaneewong, Surin Numkanisorn, Keerati Chareancholvanich, Thossart Harnroongroj DOI:10.4103/0019-5413.98833 PMID:22912522Background: Medial opening wedge high tibial osteotomy (MOWHTO) has proven to be an effective treatment for varus osteoarthritic knees. Various methods of fixation with different implant types and using either bone grafts or bone substitutes have been reported. We performed non-locking T-buttress plate fixation with autologous iliac bone graft augmentation, which is defined here as the traditional method, and locking compression plate fixation without any bone graft or bone substitute. We aimed to compare bone union and complications of these two MOWHTO techniques.
Materials and Methods: Between June 2005 and December 2007, 50 patients who underwent MOWHTO (a total of 60 knees) were retrospectively reviewed and classified into two groups: group A, which consisted of 26 patients (30 knees) was treated using T-buttress plate fixation with autologous iliac bone graft augmentation and group B, which consisted of 24 patients (30 knees) was operated upon using a medial high tibial locking compression plate without any augmentation. Demographic characteristics and radiographic outcomes, including union rate, time to union, medial osteotomy defects, and complications, were collected and compared between the two groups. The progress of all patients was followed for at least 2 years.
Results: All osteotomies united within 12 weeks after surgery. Group B had slightly longer time to union than group A (10.3 weeks and 9.5 weeks, respectively; P = 0.125). A significantly higher incidence of medial defects after osteotomy was reported in the locking compression plate group (P = 0.001). A total of 5 (8.3%) knees had complications. In group A, one knee had a superficial wound infection and another knee had a lateral tibial plateau fracture without significant loss of correction. In group B, one knee had screw penetration into the knee joint and two knees had local irritation that required the removal of the hardware.
Conclusion: Locking compression plate fixation without the use of bone grafts or bone substitutes provides a satisfactory union rate and an acceptable complication rate when compared to the traditional MOWHTO technique. Thus, we recommend using this technique for treating unicompartmental medial knee osteoarthritis. |
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Soft tissue coverage in open fractures of tibia |
p. 462 |
Jagannath B Kamath, M Shantaram Shetty, Thangam Verghese Joshua, Ajith Kumar, Harshvardhan , Deepak M Naik DOI:10.4103/0019-5413.97265 PMID:22912523Background: The treatment of Gustilo Anderson type 3B open fracture tibia is a major challenge and it needs aggressive debridement, adequate fixation, and early flap coverage of soft tissue defect. The flaps could be either nonmicrovascular which are technically less demanding or microvascular which has steep learning curve and available only in few centers. An orthopedic surgeon with basic knowledge of the local vascular anatomy required to harvest an appropriate local or regional flap will be able to manage a vast majority of open fracture tibia, leaving the very few complicated cases needing a free microvascular flap to be referred to specialized tertiary center. This logical approach to the common problem will also lessen the burden on the higher tertiary centers. We report a retrospective study of open fractures of leg treated by nonmicrovascular flaps to analyze (1) the role of nonmicrovascular flap coverage in type 3B open tibial fractures; (2) to suggest a simple algorithm of different nonmicrovascular flaps in different zones and compartment of the leg, and to (3) analyze the final outcome with regards to time taken for union and complications.
Materials and Methods: One hundered and fifty one cases of Gustilo Anderson type 3B open fracture tibia which needed flap cover for soft tissue injury were included in the study. Ninety four cases were treated in acute stage by debridement; fracture fixation and early flap cover within 10 days. Thirty-eight cases were treated between 10 days to 6 weeks in subacute stage. The rest 19 cases were treated in chronic stage after 6 weeks. The soft tissue defect was treated by various nonmicrovascular flaps depending on the location of the defect.
Results: All 151 cases were followed till the raw areas were covered. In seven cases secondary flaps were required when the primary flaps failed either totally or partially. Ten patients underwent amputation. Twenty-two patients were lost to followup after the wound coverage. Out of the remaining 119 patients, 76 achieved primary acceptable union and 43 patients went into delayed or nonunion. These 43 patients needed secondary reconstructive surgery for fracture union.
Conclusion: open fracture of the tibia which needs flap coverage should be treated with high priority of radical early debridement, rigid fixation, and early flap coverage. A majority of these wounds can be satisfactorily covered with local or regional nonmicrovascular flaps. |
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Functional and oncologic outcomes after excision of the total femur in primary bone tumors: Results with a low cost total femur prosthesis |
p. 470 |
Ajay Puri, Ashish Gulia, Wai Hoong Chan DOI:10.4103/0019-5413.98834 PMID:22912524Background: The extent of tumor may necessitate resection of the complete femur rarely to achieve adequate oncologic clearance in bone sarcomas. We present our experience with reconstruction in such cases using an indigenously manufactured, low-cost, total femoral prosthesis (TFP). We assessed the complications of the procedure, the oncologic and functional outcomes, and implant survival.
Materials and Methods: Eight patients (four males and four females) with a mean age of 32 years, operated between December 2003 and June 2009, had a TFP implanted. The diagnosis included osteogenic sarcoma (5), Ewing's sarcoma (1), and chondrosarcoma (2). Mean followup was 33 months (9-72 months) for all and 40 months (24-72 months) in survivors. They were evaluated by Musculoskeletal Tumor Society score, implant survival as well as patient survival.
Results: There was one local recurrence and five of seven patients are currently alive at the time of last followup. The Musculoskeletal Tumor Society score for patients ranged from 21 to 25 with a mean of 24 (80%). The implant survival was 88% at 5 years with only one TFP needing removal because of infection.
Conclusions: A TFP in appropriately indicated patients with malignant bone tumors is oncologically safe. A locally manufactured, cost-effective implant provided consistent and predictable results after excision of the total femur with good functional outcomes. |
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| CASE REPORTS |
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Intradural extramedullary capillary hemangioma of lower thoracic spinal cord |
p. 475 |
Dhiraj Vithal Sonawane, Sanjay A Jagtap, Ambarish Avinash Mathesul DOI:10.4103/0019-5413.97262 PMID:22912525Capillary hemangiomas are benign tumors and tumor like conditions commonly involving skin and mucus membrane of head and neck region. They are extremely rare in the spinal cord. We report a 35-year-old male presenting with gradual progressive paraparesis over a period of 4 months. Magnetic resonance imaging showed a hypo- to isointense intradural mass at the level of D12 vertebral body on T1-weighted images and homogenous enhancement on gadolinium contrast. Complete surgical resection revealed intradural extramedullary tumor, which on histopathologic examination showed characteristics of capillary hemangioma. At 1.5 years followup patient was asymptomatic. |
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Infected primary non-Hodgkin lymphoma of spine |
p. 479 |
Che-Wei Liu, Tsung-Ying Tsai, Yao-Feng Li, Leou-Chyr Lin, Shyu-Jye Wang DOI:10.4103/0019-5413.98835 PMID:22912526Primary bone lymphoma (PBL) comprises less than 5% of all malignant bone tumors and almost 7% of all extranodal lymphomas. Only 1.7% of all PBLs have been reported to involve the vertebrae. In our case, osteomyelitis was accidentally found during surgery, which might have resulted in the rapid collapse of vertebral body. This is the first report on primary lymphoma of the vertebrae with superimposed osteomyelitis in the English literature to the best of our knowledge. The patient reported here received anterior vertebrectomy and posterior interbody fusion with instrumentation for spinal instability. Tumor mass and the necrotic debris were removed. After the procedure, the patient received treatment with antibiotics and six cycles of chemotherapy. This case reminds us the possibility of hematologic seeding of bacteria in the tissue, especially with tumor necrosis. We suggest percutaneous needle aspiration for pathology and culture before making a decision whether or not to proceed with surgical decompression for fear of missing the occult bacterial infection. |
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Trabecular metal acetabular revision system (cup-cage construct) to address the massive acetabular defects in revision arthroplasty |
p. 483 |
Rajesh Malhotra, Ramprasad Kancherla, Vijay Kumar, Aditya Soral DOI:10.4103/0019-5413.97264 PMID:22912527The increasing number of total hip replacements in the younger clique has added to the demand for revision procedures. Revision situations are often encountered with infection, loss of bone stock and bone defects. There are various methods of reconstruction of acetabular defects. The management options of type 3B Paprosky acetabular defects are limited with allograft and conventional cages. Trabecular metal technology has evolved to address these bone defects. Trabecular metal acetabular revision system (TMARS) cup-cage construct is a new technique to address massive acetabular defects. We describe a case of failed hip reconstruction done for a Giant cell tumour of proximal femur managed by a two stage procedure, initial debridement and second stage reconstruction of acetabulum with TMARS cup-cage construct and femur with allograft prosthesis composite. |
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Extranodal Rosai-Dorfman disease in a carpal bone |
p. 487 |
Kalpalata Tripathy, Aparijita Misra, Anil Kumar Sahu, Kaumudee Patnaik DOI:10.4103/0019-5413.98836 PMID:22912528We report a case of extranodal Rosai-Dorfman Disease (RDD) of the scophoid in a 52-year old female. The patient presented with pain, swelling, and tenderness on deep palpation of the left wrist. Clinicoradiological diagnosis was osteomyelitis or tenosynovitis and curettage was performed on the lytic lesion over scaphoid to procure tissue. Diagnosis was made by histomorphology supported by immunostaining. The patient was managed conservatively with resolution of the lesion. |
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| LETTERS TO EDITOR |
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Management of thromboangiitis obliterans using distraction osteogenesis: A retrospective study |
p. 490 |
Vikram Marwah DOI:10.4103/0019-5413.98837 PMID:22912529 |
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Author's reply |
p. 490 |
Sunil Kulkarni, Ashok K Shyam, Milind Kulkarni, Ruta Kulkarni, Vidisha Kulkarni PMID:22912530 |
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Salvage of infected total knee arthroplasty with Ilizarov external fixator |
p. 491 |
Bhaskar Borgohain DOI:10.4103/0019-5413.98839 PMID:22912531 |
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| OBITUARY |
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Prof. Balu Sankaran |
p. 492 |
| M Shantharam Shetty |
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| ERRATUM |
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Erratum |
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PMID:22912511 |
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