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Year : 2004  |  Volume : 38  |  Issue : 4  |  Page : 246-250

Sarcomatous Transformation Of Osteochondroma



Correspondence Address:
Sudhir K Kapoor


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Source of Support: None, Conflict of Interest: None


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Background: Osteochondroma is the most common benign bony tumor and has been potential for malignant transformation to usually chondrosarcoma. Methods: We report 12 cases of chondrosarcoma, developing in osteochondroma. Four patients had solitary osteochondroma and 8 patients had multiple hereditary osteochondromatosis (MHO). Recent increase in size of bony swelling and pain/discomfort were common symptoms. The diagnosis was based on plain radiograph, CT scan and MRI finding, in conjunction with histopathological evaluation particularly in grade I chondrosarcoma. Eleven patients were treated surgically-amputation was done in three, wide excision in three, marginal excision in four and debulking was done in one case. Results: Out of 12 patients, 3 have died; one patients is living with disease and remaining 8 are having disease free survival after a mean follow up of 48 months. Early timely detection and wide excision offers the best results. Conclusion: Wide surgical resection or radical excision appears to be the treatment of choice for these lesions.


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