Source of Support: None, Conflict of Interest: None
We studied the efficacy of intra-articular injection of steroids and also the factors which affect the clinical response in management of OA Knee for relief of pain in 129 patients. The study was divided in 8 groups depending on the type of steroid which was injected, the type of local anaesthetic used in conjunction with the steroid and the total volume of injection used. So, 71 patients received Triamcinolone hexacetonide (THA) and 58 patients received Methylprednisolone acetate (MPA) injection. These two steroids were mixed with local anaesthetics (either bupivacaine or lignocaine) in small and large volumes. It was found that THA was quite effective in relieving knee pain of OA as compared to MPA. At 8 weeks, following intra-articular injection, THA was twice as effective as MPA, though at 6 months this effect was still more but not significantly different. Bupivacaine had a better response in pain relief as compared to Ligocaine when used with either THA or MPA. In patients who had large volume of injections and distension of the knee joint there was better relief of symptoms of OA Knee. For giving the knee injection, infero-lateral site was found to be the most appropriate site as localization of the joint was easy and needle placement was convenient.