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This study was conducted on fifty-six patients with sixty-five total hip arthroplasties. Aim of this study was to evaluate the role of three phase bone scan in early detection of aseptic\septic loosening following total hip arhtroplasty. In this study sensitivity and specificity of plain X-ray was 40% and 100 % respectively while in case of three phase bone scan it was 100% and 84.6% respectively for diagnosis of aseptic loosening. There was only one case of infection which was not detected on plain radiographs but infection was detected on three phase bone scan. This concludes that three phase bone scan is a useful investigation in early diagnosis of aseptic loosening and occult infection however a good clinical and radiological correlation is a must. Normal three phase bone scan should be weighed heavily against surgical exploration in an attempt to find the cause of pain.
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