Source of Support: None, Conflict of Interest: None
Avascular necrosis of femoral head is a frequent and disabling manifestation in sickle cell haemoglobinopathies. Skeletal changes in sickle cell disease were observed as early as 1924 by Graham. Association of bone changes sickle cell disease was also observed by Golding (1959), Caffey (1937) and Diggs et al. (1965). The purpose of this article is to describe the clinical entity, laboratory investigations, and roentgenographic findings of sickle cell haemoglobinopathies in our cases of sickle cell anaemia and sickle cell trait causing avascular necrosis of femoral head.