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Year : 1977  |  Volume : 11  |  Issue : 1  |  Page : 93-96

Corticosteroid Therapy And Its Untoward Musculo-Skeletal Effects



Correspondence Address:
N. D Aggarwal


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Source of Support: None, Conflict of Interest: None


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Corticosteroids, the so called “Wonder Drugs” after their first discovery in 1948, had found their use for almost every conceivable malady till their hazards came to light. Besides the systemic side effects which interest the physicians, the musculo-skeletal system also manifests certain striking harmful effects, like osteoporosis with or without pathological fractures (Boland and Headley 1950, Demartini, Grokoest and Ragan 1952, Kendall and Hart 1959, Lindholim 1960) and avascular necrosis of articular ends of long bones with arthropatly (Harnagel 1962, Boksenbaum and Mendelson 1963, Cruess, Blennerhassett, Macdonald, Maclean and Dossetor 1968) muscular cramps, weakness and frank myopathies, (Golding and Begg 1960), bilateral rupture of achillis tendon (Lee 1961, Cowan and Alexander 1961). Frequent and prolonged systemic use of corticosteroids in various medical disorders and its common use as local injections by orthopaedic surgeons have prompted us to carry out this study and find out the harmful musculo-skeletal side effects.


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