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Year : 1977  |  Volume : 11  |  Issue : 1  |  Page : 56-58

A Comparative Study Of Serum Enzyme Isocitrate Dehydrogenase In Patients Having Benign And Malignant Bone Tumours



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R. S Sandhu


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Interest in serum enzymology began when diagnostic significance of alkaline phosphatase and acid phosphatase was established (Bodansky 1954). Several serum enzymes corresponding to the metabolically involved enzymes in the tissues have been recently studied as a reflection of the neoplastic process (Wroblewsky 1961, korn et al. 1962). Isocitrate dehydrogenase activity has been investigated to a limited extent in the follow up of malignancy of bone, prostate, breast, lungs, uterus, cervix etc. At present the utility of serum enzyme levels in malignancy is far from definite conclusions. The aim of this study was to find out the serum levels of the enzyme isocitrate dehydrogenase (ICDH) and its relation to the activity, treatment, and spread of growth.


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