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Year : 1977  |  Volume : 11  |  Issue : 1  |  Page : 1-19

Behaviour Of Autoclaved Massive Autologous Bone Grafts-An Experimental Study



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S. M Tuli


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For preservation of sterile bone grafts many sophisticated physical, chemical and biological methods have been employed. Boiling and autoclaving are relatively simple and easily available methods of sterilizing bone grafts. Not much work has however been reported regarding the behaviour of heat treated bone when used as a bone graft for bridging a gap. Successful application of heat-treated bone grafts may be of special significance in economically underdeveloped countries where sophisticated facilities are not available and perpetual power failures and shortage does not ensure suitable temperature for preservation in the bone banks. Many practical orthopaedic surgeons have had an occasion of using a bone graft after autoclaving or boiling in operation theatre, however only a few cases of successful use of heat treated bone in clinical practice have been reported (Thompson and Steggal 1959, Kirkup 1965, Abell 1966, Tuli 1967, Evens et al. 1969, Enneking and Flynn 1969, Lippmann 1969, Pauker 1971, Synbrandy 1973). The follow up in most of the clinical cases out of necessity was confined to radiological examination. The following experimental work was done primarily to observe the histological changes that would take place in a heat treated bone graft.


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