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According to the currently accepted criteria for diagnosis there are only a few reports of large series of giant-cell tumours reported from India. A study of 51 cases was reported by us earlier (Vyaghreswarudu 1960). The present report is based upon personal observations on 100 cases of giant-cell tumours of bone. The number of the cases available for various types of studies and follow up observations is mentioned at appropriate places. The incidence of giant-cell tumour of bone n relation to the tumours in general and tumours of the skeletal system in particular, as observed in the king George Hospital, Andhra Medical College, Visakhapatnam, during the 20 years period between 1949 and 1968 is shown in table I. Bonetumours formed 1.35 percent of all the cases of tumours of the body. Giant-cell tumours constituted nearly 28 percent of all cases of bone tumours.