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Year : 1973  |  Volume : 7  |  Issue : 1  |  Page : 107-114

Crystal Synovitis-An Experimental Study

Correspondence Address:
V. P Bansal

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Source of Support: None, Conflict of Interest: None

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In the pathogenesis of gout and pseudogout, the significance of crystals of sodium urate in the former (Faires and McCarty 1961) and calcium pyrophosphate (McCarty et al 1962, 1963) and calcium oxalate (Curry and Sweetenham 1965) in the latter has been highlighted. However, it is not known if the joint lesions seen in the humans are directly attributable to the presence of crystals or that there are some other metabolic factors involved in it. In order to elucidate the role of these crystals in producing joint lesions, the present experimental study was undertaken to study the effect of (a) sodium urate and (b) calcium oxalate crystals on the synovial membrane.

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